STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
317.t00005Ras guanine nucleotide exchange factor, putative. (440 aa)    
Predicted Functional Partners:
EHI_055350
Uncharacterized protein.
   
 0.578
30.t00036
SH3 domain-containing protein.
   
 0.578
222.t00005
BAR/SH3 domain containing protein.
   
 0.578
152.t00013
Uncharacterized protein.
   
 0.497
88.t00013
Rho guanine nucleotide exchange factor, putative.
   
 0.476
259.t00005
Protein kinase domain containing protein.
   
 0.474
298.t00004
Uncharacterized protein.
   
 0.450
150.t00018
Protein kinase, putative; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.446
189.t00011
Protein tyrosine phosphatase, putative.
   
 0.439
171.t00014
Ankyrin repeat protein, putative.
   
 0.435
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.