STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
383.t00007Rho guanine nucleotide exchange factor, putative. (254 aa)    
Predicted Functional Partners:
28.t00003
Guanine nucleotide exchange factor, putative.
    
 0.620
78.t00035
Uncharacterized protein.
    
 0.554
221.t00013
Rho guanine nucleotide exchange factor, putative.
   
0.534
84.t00019
Protein with RhoGEF and ArfGAP domains.
   
0.534
217.t00017
Uncharacterized protein.
   
 
 0.525
7.t00076
Rho guanine nucleotide exchange factor, putative.
    
0.523
150.t00017
Protein kinase, putative; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.466
150.t00018
Protein kinase, putative; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.466
22.t00018
Uncharacterized protein.
   
 0.452
395.t00002
Rho family GTPase.
   
 0.443
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.