node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFJ03124.1 | SFJ03154.1 | SAMN04488138_101246 | SAMN04488138_101247 | Transcriptional regulator, AsnC family. | DNA-binding transcriptional regulator, Lrp family. | 0.877 |
SFJ03124.1 | SFJ16767.1 | SAMN04488138_101246 | SAMN04488138_102204 | Transcriptional regulator, AsnC family. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. | 0.559 |
SFJ03124.1 | SFK00861.1 | SAMN04488138_101246 | SAMN04488138_11929 | Transcriptional regulator, AsnC family. | Aspartate aminotransferase. | 0.405 |
SFJ03124.1 | ilvC | SAMN04488138_101246 | SAMN04488138_101245 | Transcriptional regulator, AsnC family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.715 |
SFJ03154.1 | SFJ03124.1 | SAMN04488138_101247 | SAMN04488138_101246 | DNA-binding transcriptional regulator, Lrp family. | Transcriptional regulator, AsnC family. | 0.877 |
SFJ03154.1 | SFJ16767.1 | SAMN04488138_101247 | SAMN04488138_102204 | DNA-binding transcriptional regulator, Lrp family. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. | 0.559 |
SFJ03154.1 | SFK00861.1 | SAMN04488138_101247 | SAMN04488138_11929 | DNA-binding transcriptional regulator, Lrp family. | Aspartate aminotransferase. | 0.405 |
SFJ03154.1 | ilvC | SAMN04488138_101247 | SAMN04488138_101245 | DNA-binding transcriptional regulator, Lrp family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.715 |
SFJ16767.1 | SFJ03124.1 | SAMN04488138_102204 | SAMN04488138_101246 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. | Transcriptional regulator, AsnC family. | 0.559 |
SFJ16767.1 | SFJ03154.1 | SAMN04488138_102204 | SAMN04488138_101247 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. | DNA-binding transcriptional regulator, Lrp family. | 0.559 |
SFJ16767.1 | ilvC | SAMN04488138_102204 | SAMN04488138_101245 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.406 |
SFK00861.1 | SFJ03124.1 | SAMN04488138_11929 | SAMN04488138_101246 | Aspartate aminotransferase. | Transcriptional regulator, AsnC family. | 0.405 |
SFK00861.1 | SFJ03154.1 | SAMN04488138_11929 | SAMN04488138_101247 | Aspartate aminotransferase. | DNA-binding transcriptional regulator, Lrp family. | 0.405 |
ilvC | SFJ03124.1 | SAMN04488138_101245 | SAMN04488138_101246 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Transcriptional regulator, AsnC family. | 0.715 |
ilvC | SFJ03154.1 | SAMN04488138_101245 | SAMN04488138_101247 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | DNA-binding transcriptional regulator, Lrp family. | 0.715 |
ilvC | SFJ16767.1 | SAMN04488138_101245 | SAMN04488138_102204 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. | 0.406 |