STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFJ47788.1Aminomethyltransferase; Belongs to the GcvT family. (377 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 0.998
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.994
SFJ47713.1
Protein of unknown function.
   
 0.960
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 0.954
SFJ47739.1
Ferredoxin-NADP reductase.
 
 
 0.933
SFJ78211.1
Aminomethyltransferase.
  
  
 
0.931
SFJ58383.1
Dihydrolipoamide dehydrogenase.
 
  0.928
SFJ47760.1
Hypothetical protein.
 
   
 0.904
folD-2
Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 
 0.878
SFJ48262.1
Aminomethyltransferase; Belongs to the GcvT family.
 
  
 
0.864
Your Current Organism:
Celeribacter halophilus
NCBI taxonomy Id: 576117
Other names: C. halophilus, CGMCC 1.8891, Celeribacter halophilus (Wang et al. 2012) Lai et al. 2014, DSM 26270, Huaishuia halophila, Huaishuia halophila Wang et al. 2012, LMG 24854, LMG:24854, MCCC 1A06432, Pseudoruegeria sp. ZXM137, strain ZXM137
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