STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDK42539.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)    
Predicted Functional Partners:
SDK42570.1
Aspartate aminotransferase.
 
 
 0.987
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.912
SDL05673.1
Glyoxalase family protein.
    
  0.901
gpmI
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.892
SDK19885.1
Acetolactate synthase, small subunit.
 
 
 0.884
SDK27694.1
Homoserine dehydrogenase.
  
 0.845
SDK41566.1
Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like.
  
 0.839
SDK24805.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.831
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.802
SDK69996.1
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.797
Your Current Organism:
Salinicoccus qingdaonensis
NCBI taxonomy Id: 576118
Other names: CGMCC 1.8895, LMG 24855, LMG:24855, S. qingdaonensis, Salinicoccus qingdaonensis Qu et al. 2012, Salinicoccus sp. ZXM223, strain ZXM223
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