node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDY17559.1 | SDY18928.1 | SAMN05444486_101588 | SAMN05444486_101659 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP. | 0.950 |
SDY17559.1 | clpS | SAMN05444486_101588 | SAMN05444486_10159 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.989 |
SDY17559.1 | dnaK | SAMN05444486_101588 | SAMN05444486_10420 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.993 |
SDY17559.1 | groS | SAMN05444486_101588 | SAMN05444486_102121 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.796 |
SDY17559.1 | grpE | SAMN05444486_101588 | SAMN05444486_103690 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.931 |
SDY17559.1 | hrcA | SAMN05444486_101588 | SAMN05444486_103689 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.719 |
SDY17559.1 | hslV | SAMN05444486_101588 | SAMN05444486_103656 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | HslV component of HslUV peptidase. Threonine peptidase. MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.632 |
SDY18928.1 | SDY17559.1 | SAMN05444486_101659 | SAMN05444486_101588 | ATP-dependent Clp protease proteolytic subunit ClpP. | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | 0.950 |
SDY18928.1 | SDY18942.1 | SAMN05444486_101659 | SAMN05444486_101660 | ATP-dependent Clp protease proteolytic subunit ClpP. | Nucleotide-binding universal stress protein, UspA family. | 0.714 |
SDY18928.1 | clpB | SAMN05444486_101659 | SAMN05444486_103270 | ATP-dependent Clp protease proteolytic subunit ClpP. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.951 |
SDY18928.1 | clpS | SAMN05444486_101659 | SAMN05444486_10159 | ATP-dependent Clp protease proteolytic subunit ClpP. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.704 |
SDY18928.1 | clpX | SAMN05444486_101659 | SAMN05444486_1011047 | ATP-dependent Clp protease proteolytic subunit ClpP. | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.998 |
SDY18928.1 | dnaK | SAMN05444486_101659 | SAMN05444486_10420 | ATP-dependent Clp protease proteolytic subunit ClpP. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.750 |
SDY18928.1 | groS | SAMN05444486_101659 | SAMN05444486_102121 | ATP-dependent Clp protease proteolytic subunit ClpP. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.700 |
SDY18928.1 | grpE | SAMN05444486_101659 | SAMN05444486_103690 | ATP-dependent Clp protease proteolytic subunit ClpP. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.704 |
SDY18928.1 | hrcA | SAMN05444486_101659 | SAMN05444486_103689 | ATP-dependent Clp protease proteolytic subunit ClpP. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.782 |
SDY18928.1 | hslV | SAMN05444486_101659 | SAMN05444486_103656 | ATP-dependent Clp protease proteolytic subunit ClpP. | HslV component of HslUV peptidase. Threonine peptidase. MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.660 |
SDY18942.1 | SDY18928.1 | SAMN05444486_101660 | SAMN05444486_101659 | Nucleotide-binding universal stress protein, UspA family. | ATP-dependent Clp protease proteolytic subunit ClpP. | 0.714 |
clpB | SDY18928.1 | SAMN05444486_103270 | SAMN05444486_101659 | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP. | 0.951 |
clpB | clpS | SAMN05444486_103270 | SAMN05444486_10159 | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.966 |