STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC_19269Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (902 aa)    
Predicted Functional Partners:
PAC_07196
Small subunit of ribonucleotide reductase.
  
 0.998
PAC_10786
Related to glutaredoxin.
  
 0.973
PAC_16154
Probable glutaredoxin Grx1.
  
 0.973
PAC_00269
DNA helicase; Belongs to the MCM family.
   
 
 0.945
PAC_17643
Probable CDC21-thymidylate synthase.
  
  
 0.944
PAC_06704
DNA helicase; Belongs to the MCM family.
   
 
 0.931
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.929
PAC_13142
DNA helicase; Belongs to the MCM family.
   
 
 0.919
PAC_03175
DNA helicase; Belongs to the MCM family.
   
  
 0.916
PAC_06345
Related to thymidylate kinase.
  
 
 0.913
Your Current Organism:
Phialocephala subalpina
NCBI taxonomy Id: 576137
Other names: P. subalpina
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