STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC_19926Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (485 aa)    
Predicted Functional Partners:
PAC_08187
Probable oxoglutarate dehydrogenase.
  
 0.976
PAC_01919
Probable 3-methyl-2-oxobutanoate dehydrogenase (Lipoamide)E1 beta chain.
 
 0.973
PAC_19927
Related to 3-methyl-2-oxobutanoate dehydrogenase.
 
 0.972
PAC_19928
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.963
PAC_02064
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.962
PAC_12757
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.961
PAC_07305
Dihydrolipoyl dehydrogenase.
 
 0.942
PAC_06018
Zn(2)-C6 fungal-type domain-containing protein.
  
 0.915
PAC_07629
Related to LPD1-dihydrolipoamide dehydrogenase.
  
 0.915
PAC_15776
Uncharacterized protein.
  
 0.915
Your Current Organism:
Phialocephala subalpina
NCBI taxonomy Id: 576137
Other names: P. subalpina
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.