STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2UZR8_NAEGRProliferating-cell nucleolar antigen p120; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (702 aa)    
Predicted Functional Partners:
D2VM15_NAEGR
Predicted protein.
   
 
 0.961
D2UXU6_NAEGR
Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.
   
 
 0.959
D2V1Q2_NAEGR
Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.
  
 
 0.959
D2VGI9_NAEGR
Predicted protein.
   
 
 0.959
D2UY25_NAEGR
Nucleolar complex protein 2.
   
 
 0.956
D2V3B4_NAEGR
Nucleostemin family protein.
   
 
 0.956
D2UXP1_NAEGR
Brix domain-containing protein.
   
 
 0.954
D2V7G4_NAEGR
Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
  
 
 0.954
D2VN86_NAEGR
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.944
D2VG53_NAEGR
Predicted protein.
   
 
 0.938
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.