STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2UZS3_NAEGRPredicted protein. (395 aa)    
Predicted Functional Partners:
D2VPH4_NAEGR
Predicted protein.
   
 0.971
D2UZM5_NAEGR
5'-nucleotidase.
     
 0.923
D2VMB8_NAEGR
Predicted protein.
     
 0.923
D2VUA6_NAEGR
Predicted protein.
  
  
 
0.920
D2V3F7_NAEGR
Predicted protein.
  
  
 
0.919
D2V6J0_NAEGR
Predicted protein.
     
 0.900
D2W4C0_NAEGR
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
  
 0.834
D2UZZ4_NAEGR
Predicted protein.
  
 0.806
D2VQ73_NAEGR
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.732
D2VQY1_NAEGR
Phosphoribosyltransferase.
  
 0.714
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.