STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2V1F4_NAEGRMethylmalonate-semialdehyde dehydrogenase. (528 aa)    
Predicted Functional Partners:
D2VYJ6_NAEGR
Predicted protein.
   
 0.966
D2W3Y5_NAEGR
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
   
 0.966
D2UY50_NAEGR
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.949
D2V498_NAEGR
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 
 0.945
D2VWR0_NAEGR
Predicted protein.
   
 0.945
D2UZI7_NAEGR
Predicted protein; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.937
D2V786_NAEGR
Predicted protein; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.937
D2VV98_NAEGR
Predicted protein; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.935
D2W1J9_NAEGR
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
0.935
D2VIL4_NAEGR
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
0.934
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.