STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2V2D9_NAEGRHistone H3. (109 aa)    
Predicted Functional Partners:
D2VCV0_NAEGR
Predicted protein.
   
 0.888
D2VJX6_NAEGR
F-box domain-containing protein.
   
 0.888
D2VSM5_NAEGR
F-box domain-containing protein.
   
 0.888
D2VZ29_NAEGR
Predicted protein.
   
 
 0.855
D2V5L9_NAEGR
Histone H2A; Belongs to the histone H2A family.
   
 0.819
D2V7R9_NAEGR
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.777
D2VUK5_NAEGR
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.777
D2VDS9_NAEGR
Histone H2B; Belongs to the histone H2B family.
   
 0.765
D2W0W4_NAEGR
Histone H2B; Belongs to the histone H2B family.
   
 0.765
D2VBF3_NAEGR
Histone acetyltransferase gcn5.
    
 0.758
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.