STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2V447_NAEGRAminotransferase. (793 aa)    
Predicted Functional Partners:
D2V1Q2_NAEGR
Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.
   
  
 0.624
D2VIP5_NAEGR
tRNA (guanine(46)-N(7))-methyltransferase.
  
  
 0.595
D2VEM9_NAEGR
Predicted protein.
  
  
 0.579
D2V2P3_NAEGR
Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.
   
 
 0.571
D2VCK4_NAEGR
Predicted protein.
   
 
 0.569
D2V1M8_NAEGR
Predicted protein.
  
  
 0.568
D2UZ28_NAEGR
ATP-dependent RNA helicase.
  
  
 0.565
D2VIF3_NAEGR
Adenylyltransferase and sulfurtransferase MOCS3 homolog; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards U [...]
  
 
 0.552
D2VXA5_NAEGR
tRNA (adenine(58)-N(1))-methyltransferase.
  
  
 0.542
NAEGRDRAFT_924
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
  0.534
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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