STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2V558_NAEGRPredicted protein. (538 aa)    
Predicted Functional Partners:
D2V0B2_NAEGR
Thiamine-phosphate pyrophosphorylase.
 
 
 0.937
D2VXT5_NAEGR
[Fe]-hydrogenase maturation protein HydG.
  
 
 0.895
D2UXH8_NAEGR
DNA polymerase.
 
      0.803
D2UYR5_NAEGR
Pyridoxine kinase.
   
 
 0.793
D2VXT6_NAEGR
[Fe] hydrogenase maturation protein.
  
  
 0.776
D2VMI7_NAEGR
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
  
 0.744
D2VBL0_NAEGR
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
     
 0.728
D2V1L2_NAEGR
Predicted protein.
     
 0.721
D2VIX8_NAEGR
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
    
 0.701
D2VPH4_NAEGR
Predicted protein.
    
 0.701
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.