STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2VB40_NAEGRThioredoxin domain-containing protein. (144 aa)    
Predicted Functional Partners:
D2VAG9_NAEGR
Predicted protein.
  
 0.878
D2V019_NAEGR
Methionine sulfoxide reductase A.
   
 0.860
D2V4S4_NAEGR
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.820
D2W225_NAEGR
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.768
D2V520_NAEGR
Predicted protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.715
D2V6C0_NAEGR
Predicted protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.715
D2VLQ6_NAEGR
Thioredoxin reductase.
  
 0.715
D2V4N1_NAEGR
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.709
D2V7X8_NAEGR
Predicted protein.
  
 
 0.709
D2V0Z9_NAEGR
Calreticulin.
   
 0.657
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.