STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2VEG5_NAEGRPredicted protein. (271 aa)    
Predicted Functional Partners:
D2W4C0_NAEGR
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
   
 
 0.725
D2VP10_NAEGR
Predicted protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.606
D2VRD7_NAEGR
Isocitrate dehydrogenase NADP-dependent.
 
 
 
 0.586
D2V2J3_NAEGR
3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.577
D2W1J9_NAEGR
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.551
D2VF59_NAEGR
Short chain dehydrogenase/reductase.
 
 0.540
D2V2C0_NAEGR
Nitrate reductase.
  
 0.535
D2W074_NAEGR
Predicted protein; Belongs to the cytochrome b5 family.
  
 0.535
D2VKA5_NAEGR
Acyl-CoA dehydrogenase family member.
  
 0.524
D2W323_NAEGR
Predicted protein.
  
 0.520
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.