STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2VJF9_NAEGRRhoGEF domain-containing protein. (895 aa)    
Predicted Functional Partners:
D2UXF7_NAEGR
Predicted protein.
   
 0.997
D2V7Y1_NAEGR
EF-hand domain-containing protein.
   
 0.997
D2VDB8_NAEGR
Uncharacterized protein.
   
 0.997
D2UXT4_NAEGR
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.996
NAEGRDRAFT_503
Predicted protein.
    
 0.996
D2VMT9_NAEGR
AP complex subunit beta.
    
 0.996
D2VV63_NAEGR
Predicted protein; Belongs to the adaptor complexes medium subunit family.
    
 0.996
D2V5V4_NAEGR
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.995
D2VAB5_NAEGR
Predicted protein.
    
 0.992
D2VKP7_NAEGR
Predicted protein.
    
 0.992
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.