STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2VJV7_NAEGRAldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (515 aa)    
Predicted Functional Partners:
D2V4E7_NAEGR
Alcohol dehydrogenase.
 
 0.736
D2VGV4_NAEGR
Predicted protein.
  
 0.693
D2UXY5_NAEGR
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.681
D2V2C0_NAEGR
Nitrate reductase.
  
 0.652
D2W074_NAEGR
Predicted protein; Belongs to the cytochrome b5 family.
  
 0.652
D2UZH1_NAEGR
Fumarylacetoacetate hydrolase.
  
 0.647
D2V650_NAEGR
Predicted protein.
  
 0.647
D2VEG9_NAEGR
Predicted protein.
  
 0.642
D2V853_NAEGR
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
  
 0.636
D2UY50_NAEGR
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.633
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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