STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2VUA2_NAEGRARF/SAR family small GTPase. (665 aa)    
Predicted Functional Partners:
D2VHR3_NAEGR
Predicted protein; Belongs to the protein kinase superfamily.
    
 0.982
D2VYD0_NAEGR
Predicted protein.
   
 0.804
D2W548_NAEGR
Predicted protein.
    
 0.786
D2VUG5_NAEGR
Predicted protein.
   
 0.659
D2VEN0_NAEGR
RhoGEF domain-containing protein.
    
 0.643
D2VJF9_NAEGR
RhoGEF domain-containing protein.
    
 0.643
D2W169_NAEGR
Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
    
 0.626
D2VRU3_NAEGR
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.574
D2VFZ7_NAEGR
ArfGTPase-activating protein.
   
 0.570
D2VSA0_NAEGR
Predicted protein; Belongs to the PI3/PI4-kinase family.
    
 0.555
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.