STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2W4D9_NAEGRMalic enzyme. (636 aa)    
Predicted Functional Partners:
D2VYA7_NAEGR
Fumarase class II.
  
 
 0.977
D2W2J6_NAEGR
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.970
D2UY48_NAEGR
Fumarate hydratase class I.
  
 
 0.967
D2V449_NAEGR
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.959
D2V4P7_NAEGR
Malate dehydrogenase.
  
 0.955
D2VA17_NAEGR
Malate dehydrogenase.
  
 0.955
D2VZB1_NAEGR
Malate dehydrogenase.
  
 0.955
D2VGQ5_NAEGR
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.954
D2VQJ9_NAEGR
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.936
D2VW96_NAEGR
Malic enzyme.
  
  
 
0.906
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.