STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDD74634.1Diguanylate cyclase (GGDEF) domain-containing protein. (292 aa)    
Predicted Functional Partners:
SDD73599.1
Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains.
 
 
  0.962
SDE65170.1
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant).
 
 
 0.954
SDE13166.1
Signal transduction histidine kinase.
  
 0.940
SDD70114.1
Two component transcriptional regulator, winged helix family.
 
 
 
  0.919
SDD91254.1
Signal transduction histidine kinase.
 
 0.896
SDD71579.1
HDIG domain-containing protein.
 
 
  0.893
SDD97919.1
Diguanylate cyclase (GGDEF) domain-containing protein.
 
0.885
SDE43530.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
 
0.868
SDD82636.1
HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant).
 
 
 0.862
SDE25888.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
 
0.838
Your Current Organism:
Desulfuromonas thiophila
NCBI taxonomy Id: 57664
Other names: D. thiophila, DSM 8987, strain NZ27
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.