STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDE27782.1HD-like signal output (HDOD) domain, no enzymatic activity. (292 aa)    
Predicted Functional Partners:
SDE27815.1
Two-component system, chemotaxis family, response regulator CheY.
 
     0.815
SDE27848.1
Chemotaxis phosphatase CheX.
       0.788
SDE27879.1
Response regulator receiver protein.
 
  
  0.782
cheD-2
CheD, stimulates methylation of MCP proteins; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
     0.780
SDE27687.1
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
       0.745
cheB
Two-component system, chemotaxis family, response regulator CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
       0.733
SDE27656.1
Two-component system, chemotaxis family, sensor kinase CheA.
       0.640
SDE27912.1
Chemotaxis protein CheX.
 
     0.638
SDE27946.1
Chemotaxis protein CheX.
 
     0.596
SDE43412.1
PAS domain S-box-containing protein.
 
 
  0.559
Your Current Organism:
Desulfuromonas thiophila
NCBI taxonomy Id: 57664
Other names: D. thiophila, DSM 8987, strain NZ27
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