STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEC15359.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)    
Predicted Functional Partners:
SEB31264.1
Short chain enoyl-CoA hydratase.
 
 0.995
SEB70535.1
Short chain enoyl-CoA hydratase.
 
 0.995
SEB84492.1
Acyl-coenzyme A oxidase.
  
 0.941
SEB95725.1
acetoacetyl-CoA synthetase.
  
 
 0.936
SEC08498.1
acetyl-CoA synthetase.
  
 
 0.936
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.936
SEB95525.1
acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein.
  
 0.924
SED25479.1
Biotin carboxyl carrier protein /biotin carboxylase.
  
 0.924
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.922
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.922
Your Current Organism:
Tsukamurella tyrosinosolvens
NCBI taxonomy Id: 57704
Other names: CCUG 38499, CIP 106771, DSM 44234, JCM 10112, JCM 15482 [[Tsukamurella carboxydivorans]], KCCM 42885 [[Tsukamurella carboxydivorans]], NCTC 13231, T. tyrosinosolvens, Tsukamurella carboxydivorans, Tsukamurella carboxydivorans Park et al. 2009, Tsukamurella sp. MH1, Tsukamurella sp. Y2, Tsukamurella tyrosinisolvens, strain Y2 [[Tsukamurella carboxydivorans]]
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