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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clpP-3ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (194 aa)    
Predicted Functional Partners:
SEC25643.1
ATP-dependent Clp protease, protease subunit; Belongs to the peptidase S14 family.
 
 
0.989
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
 
 0.980
clpP
ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
 
 
0.952
SED13285.1
C-terminal, D2-small domain-containing protein, of ClpB protein.
 
 
 0.757
SEB79913.1
ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.
 
 
 0.750
clpB
ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
 
 
 0.721
groS
Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
 
 
 0.721
SEC76123.1
Clp amino terminal domain-containing protein, pathogenicity island component.
 
 
 0.717
SED21598.1
Putative hydrolase.
   
  
 0.706
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
 
 
 0.702
Your Current Organism:
Tsukamurella tyrosinosolvens
NCBI taxonomy Id: 57704
Other names: CCUG 38499, CIP 106771, DSM 44234, JCM 10112, JCM 15482 [[Tsukamurella carboxydivorans]], KCCM 42885 [[Tsukamurella carboxydivorans]], NCTC 13231, T. tyrosinosolvens, Tsukamurella carboxydivorans, Tsukamurella carboxydivorans Park et al. 2009, Tsukamurella sp. MH1, Tsukamurella sp. Y2, Tsukamurella tyrosinisolvens, strain Y2 [[Tsukamurella carboxydivorans]]
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