STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OJG09314.12,3-cyclic-nucleotide 2-phosphodiesterase; Belongs to the 5'-nucleotidase family. (519 aa)    
Predicted Functional Partners:
udk
Uridine kinase.
  
 
 0.912
OJG10166.1
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.902
OJG10158.1
Pyrimidine-nucleoside phosphorylase.
    
 0.896
OJG10160.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.895
deoD
Purine nucleoside phosphorylase.
    
  0.893
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.798
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.796
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
 
  
 0.792
cinA
Competence/damage-inducible protein CinA domain; Belongs to the CinA family.
   
 
  0.792
OJG09907.1
Hypothetical protein.
    
 0.786
Your Current Organism:
Enterococcus asini
NCBI taxonomy Id: 57732
Other names: ATCC 700915, CCUG 44928, DSM 11492, E. asini, Enterococcus asinus, LMG 18727, LMG:18727, NBRC 100681, strain AS2
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