STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16216.1COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: dak:DaAHT2_1913 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit. (113 aa)    
Predicted Functional Partners:
ADW19084.1
COGs: COG0342 Preprotein translocase subunit SecD; InterPro IPR003335: IPR005791: IPR005665; KEGG: dps:DP0806 protein-export membrane protein SecD; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: Related to protein-export membrane protein SecD; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF.
 
 
 0.996
ADW16952.1
Preprotein translocase, SecE subunit; InterPro IPR001901: IPR005807; KEGG: dps:DP1111 preprotein translocase SecE subunit (partial length); PFAM: protein secE/sec61-gamma protein; SPTR: Related to preprotein translocase secE subunit (Partial length); TIGRFAM: preprotein translocase, SecE subunit; manually curated; PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial.
   
 
 0.955
ADW19288.1
Protein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
   
 
 0.946
ADW18768.1
COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR013308: IPR019998: IPR020001; KEGG: dps:DP0855 hypothetical protein; PFAM: 60 kDa inner membrane insertion protein; SPTR: Conserved hypothetical membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; membrane protein insertase, YidC/Oxa1 family domain containing; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; membrane protein insertase, YidC/Oxa1 family, N-terminal domain.
 
 
 0.944
secY
Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.942
ADW17220.1
Signal recognition particle-docking protein FtsY; COGs: COG0552 Signal recognition particle GTPase; InterPro IPR003593: IPR013822: IPR000897: IPR004390; KEGG: dps:DP2936 cell division protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase; SPTR: Cell division transporter substrate-binding protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; TIGRFAM: signal recognition particle-dockin [...]
 
  
 0.942
ADW19276.1
COGs: COG1314 Preprotein translocase subunit SecG; InterPro IPR004692; KEGG: dak:DaAHT2_0038 preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; SPTR: Preprotein translocase, SecG subunit; TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit.
  
 
 0.940
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
  
  
 0.938
ffh
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...]
    
 0.930
ADW16215.1
tRNA-guanine transglycosylase; COGs: COG0343 Queuine/archaeosine tRNA-ribosyltransferase; InterPro IPR004803: IPR002616; KEGG: dak:DaAHT2_1914 queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase; PRIAM: tRNA-guanine transglycosylase; SPTR: Queuine tRNA-ribosyltransferase; TIGRFAM: queuine tRNA-ribosyltransferase; tRNA-guanine transglycosylase, various specificities; PFAM: Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming.
  
    0.870
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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