Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW16225.1COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR018170: IPR020471: IPR001395; KEGG: abo:ABO_2414 aldehyde reductase; PFAM: aldo/keto reductase; PRIAM: Aldehyde reductase; SPTR: Oxidoreductase, aldo/keto reductase family; PFAM: Aldo/keto reductase family. (317 aa)    
Predicted Functional Partners:
ADW17789.1
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670: IPR018211; KEGG: dma:DMR_01890 dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase.
   
 0.915
ADW18151.1
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: dps:DP0955 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Probable iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase.
   
 0.915
ADW18339.1
Nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732: IPR014026: IPR014027: IPR017476; KEGG: dak:DaAHT2_1793 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose d [...]
  
 
 0.825
ADW18038.1
Trehalose-phosphatase; COGs: COG1877 Trehalose-6-phosphatase; InterPro IPR003337: IPR006379; KEGG: sat:SYN_02627 trehalose 6-phosphate phosphatase; PFAM: trehalose-phosphatase; SPTR: Trehalose 6-phosphate phosphatase; TIGRFAM: trehalose-phosphatase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Trehalose-phosphatase; TIGRFAM: trehalose-phosphatase; HAD-superfamily hydrolase, subfamily IIB.
   
   0.763
ADW16224.1
ABC transporter related protein; COGs: COG1119 ABC-type molybdenum transport system ATPase component/photorepair protein PhrA; InterPro IPR017871: IPR003439: IPR003593; KEGG: dat:HRM2_21060 ModF; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ModF; PFAM: ABC transporter.
       0.757
ADW16467.1
Putative serine protein kinase, PrkA; COGs: COG2766 Putative Ser protein kinase; InterPro IPR013153: IPR010650; KEGG: ppd:Ppro_1718 putative serine protein kinase, PrkA; PFAM: PrkA AAA domain protein; PrkA serine kinase; SMART: PrkA AAA domain protein; SPTR: Putative serine protein kinase, PrkA; PFAM: PrkA AAA domain; PrkA serine protein kinase C-terminal domain.
   
    0.746
ADW16470.1
Putative serine protein kinase, PrkA; COGs: COG2766 Putative Ser protein kinase; InterPro IPR013153; KEGG: gur:Gura_4311 putative serine protein kinase, PrkA; PFAM: PrkA AAA domain protein; SMART: PrkA AAA domain protein; SPTR: Putative serine protein kinase, PrkA; PFAM: PrkA AAA domain; PrkA serine protein kinase C-terminal domain.
   
    0.746
ADW18078.1
COGs: COG0225 Peptide methionine sulfoxide reductase; InterPro IPR002569: IPR002579; KEGG: tau:Tola_0999 methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; Methionine sulfoxide reductase A; PRIAM: Peptide-methionine (S)-S-oxide reductase., Peptide-methionine (R)-S-oxide reductase; SPTR: Methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; peptide methionine sulfoxide reductase; PFAM: SelR domain; Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; methionine-R-sulfoxide reductase.
  
  
 0.565
ADW18738.1
Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726; KEGG: dps:DP2201 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: Related to 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: Homocysteine S-methyltransferase.
   
 0.546
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
  
 
 0.497
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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