Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW16228.1Fumarase; COGs: COG0114 Fumarase; InterProIPR020557: IPR000362: IPR003031: IPR005677: IPR 018951; KEGG: dap:Dacet_2357 fumarate hydratase, class II; PFAM: fumarate lyase; Fumarase C-like; SPTR: Fumarate hydratase, class II; TIGRFAM: fumarate hydratase, class II; PFAM: Lyase; Fumarase C C-terminus; TIGRFAM: fumarate hydratase, class II. (468 aa)    
Predicted Functional Partners:
ADW18893.1
COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR001557: IPR010945: IPR001236; KEGG: dps:DP0661 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase; SPTR: Malate dehydrogenase; TIGRFAM: malate dehydrogenase; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: malate dehydrogenase.
  
 0.990
ADW18491.1
COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953: IPR004112: IPR011280; KEGG: dps:DP2136 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase; SPTR: Probable succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup.
 
 0.983
ADW16573.1
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.972
ADW18147.1
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterProIPR001891: IPR000209: IPR015884: IPR012301: IPR 012302; KEGG: dal:Dalk_0610 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; SPTR: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
 
 0.971
ADW16465.1
COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: sfu:Sfum_2105 citrate (Si)-synthase; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Citrate synthase; PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II.
   
 0.969
ADW16919.1
COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR010953: IPR019810; KEGG: dps:DP1088 citrate synthase; PFAM: Citrate synthase; SPTR: Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type).
   
 0.969
ADW17658.1
COGs: COG0372 Citrate synthase; InterPro IPR011278: IPR002020: IPR019810; KEGG: bts:Btus_2368 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II.
   
 0.969
ADW18492.1
COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR017896: IPR006058: IPR017900; KEGG: dps:DP2137 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; SPTR: Probable succinate dehydrogenase, iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 0.969
ADW18964.1
Succinate semialdehyde dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160: IPR010102; KEGG: rce:RC1_1593 succinate-semialdehyde dehydrogenase (NADP+); PFAM: Aldehyde Dehydrogenase; SPTR: Succinate-semialdehyde dehydrogenase (NADP+); TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase.
   
 0.969
ADW19371.1
Aconitase; COGs: COG1048 Aconitase A; InterPro IPR001030: IPR000573: IPR006249: IPR018136; KEGG: sth:STH3164 aconitate hydratase; PFAM: aconitate hydratase domain-containing protein; SPTR: Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase 1.
  
 0.955
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.