STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16233.1Twitching motility protein; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR003593: IPR006321: IPR001482; KEGG: dps:DP0896 twitching mobility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase; SPTR: Probable twitching mobility protein; TIGRFAM: twitching motility protein; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT. (390 aa)    
Predicted Functional Partners:
ADW16843.1
General secretion pathway protein F; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076: IPR003004: IPR011850: IPR001992; KEGG: dol:Dole_1045 general secretion pathway protein F; PFAM: Type II secretion system F domain; SPTR: General secretion pathway protein F; TIGRFAM: general secretion pathway protein F; PFAM: Bacterial type II secretion system protein F domain; TIGRFAM: general secretion pathway protein F.
  
 0.822
ADW18341.1
Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR003004: IPR018076; KEGG: dps:DP2782 type 4 fimbrial assembly protein (PilC); PFAM: Type II secretion system F domain; SPTR: Probable type 4 fimbrial assembly protein (PilC); PFAM: Bacterial type II secretion system protein F domain.
  
 0.822
ADW16478.1
COGs: COG1989 Type II secretory pathway prepilin signal peptidase PulO and related peptidase; InterPro IPR014032: IPR010627: IPR000045; KEGG: dps:DP3017 type IV prepilin leader peptidase; PFAM: peptidase A24A domain protein; peptidase A24A prepilin type IV; PRIAM: Prepilin peptidase; SPTR: Related to type IV prepilin leader peptidase; PFAM: Bacterial Peptidase A24 N-terminal domain; Type IV leader peptidase family.
 
   
 0.813
ADW16234.1
KEGG: dak:DaAHT2_1493 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.721
ADW19349.1
COGs: COG4972 Tfp pilus assembly protein ATPase PilM; InterPro IPR005883; KEGG: dps:DP0108 fimbrial assembly protein PilM; SPTR: Related to fimbrial assembly protein PilM; TIGRFAM: type IV pilus assembly protein PilM; PFAM: Competence protein A; Cell division protein FtsA; TIGRFAM: type IV pilus assembly protein PilM.
 
   
 0.709
ADW16542.1
InterPro IPR007831; KEGG: bts:Btus_3123 type II secretion system protein E; PFAM: General secretory system II protein E domain protein; SPTR: Type II secretion system protein E; PFAM: GSPII_E N-terminal domain.
 
  
 0.557
ilvD
COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR020558: IPR004404: IPR000581; KEGG: pdi:BDI_2073 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
       0.554
pilB
Cyclic nucleotide-binding protein; COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterProIPR000595: IPR007831: IPR001482: IPR003593: IPR 013374; KEGG: dps:DP2226 type IV pilus assembly protein (TapB); PFAM: type II secretion system protein E; General secretory system II protein E domain protein; cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; AAA ATPase; SPTR: Probable type IV pilus assembly protein (TapB); TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: GSPII_E N-terminal domain; Type II/IV secretion system protein; Cycli [...]
 
  
0.493
ADW19345.1
Secretin/TonB short domain protein; InterPro IPR011662: IPR013026; KEGG: dps:DP0112 fimbrial assembly protein PilQ [precursor]; PFAM: Secretin/TonB short domain; SPTR: Related to fimbrial assembly protein PilQ [Precursor]; PFAM: Secretin and TonB N terminus short domain; Localisation of periplasmic protein complexes.
     
 0.462
ADW18470.1
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477: IPR004797; KEGG: dps:DP1704 ComE operon protein 3; PFAM: ComEC/Rec2-related protein; SPTR: Related to ComE operon protein 3; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
     
 0.458
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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