STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16247.1Protein of unknown function DUF534; COGs: COG2984 ABC-type uncharacterized transport system periplasmic component; InterPro IPR007487; KEGG: dba:Dbac_0180 hypothetical protein; PFAM: protein of unknown function DUF534; SPTR: Putative uncharacterized protein; PFAM: ABC transporter substrate binding protein. (341 aa)    
Predicted Functional Partners:
ADW16246.1
Integral membrane sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR001789: IPR003660: IPR 003661: IPR003594; KEGG: sat:SYN_00568 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; response regulator receive [...]
       0.796
ADW17281.1
InterPro IPR011701; KEGG: dba:Dbac_3395 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily.
 
   
 0.409
ADW16249.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752: IPR002880; KEGG: dat:HRM2_42780 PorA3; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: PorA3; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.
       0.405
ADW16248.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR017900: IPR000759: IPR017896: IPR013027; KEGG: dat:HRM2_42770 GltD3; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: GltD3; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
       0.401
ADW16250.1
2-oxoglutarate synthase; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: dat:HRM2_42790 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM: 2-oxoglutarate synthase; SPTR: PorB4; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
       0.401
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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