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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ADW16258.1Ste24 endopeptidase; COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR001915; KEGG: cts:Ctha_1055 STE24 endopeptidase; PFAM: peptidase M48 Ste24p; PRIAM: Ste24 endopeptidase; SPTR: Ste24 endopeptidase; PFAM: Peptidase family M48. (420 aa)    
Predicted Functional Partners:
ADW16259.1
KEGG: dak:DaAHT2_1984 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: SprT-like family; Protein of unknown function (DUF2786).
       0.773
ADW16260.1
COGs: COG1166 Arginine decarboxylase (spermidine biosynthesis); InterPro IPR000183: IPR002985; KEGG: dvl:Dvul_2517 arginine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: Arginine decarboxylase; TIGRFAM: arginine decarboxylase; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: arginine decarboxylase, biosynthetic.
     
 0.652
ADW18377.1
Surface presentation of antigens (SPOA) protein; COGs: COG1868 Flagellar motor switch protein; InterPro IPR001689: IPR001543; KEGG: drt:Dret_0581 flagellar motor switch protein FliM; PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; SPTR: Flagellar motor switch protein FliM; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.
    
   0.647
ADW18389.1
COGs: COG4786 Flagellar basal body rod protein; InterPro IPR001444: IPR010930: IPR020013; KEGG: dps:DP2680 flagellar basal-body rod protein (FlgF); PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; SPTR: Related to flagellar basal-body rod protein (FlgF); TIGRFAM: flagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; flagellar hook-basal body proteins.
    
   0.647
ADW16558.1
Membrane protease FtsH catalytic subunit; COGs: COG0465 ATP-dependent Zn protease; InterProIPR005936: IPR003959: IPR000642: IPR003960: IPR 003593; KEGG: mfa:Mfla_1168 FtsH-2 peptidase; PFAM: peptidase M41; AAA ATPase central domain protein; PRIAM: Microtubule-severing ATPase; SMART: AAA ATPase; SPTR: FtsH-2 peptidase. Metallo peptidase. MEROPS family M41; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH.
   
 0.641
ADW16800.1
Membrane protease FtsH catalytic subunit; COGs: COG0465 ATP-dependent Zn protease; InterProIPR003959: IPR000642: IPR005936: IPR003960: IPR 003593; KEGG: gsu:GSU1809 cell division protein FtsH; PFAM: peptidase M41; AAA ATPase central domain protein; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: Cell division protein FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH.
   
 0.641
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.641
ADW18353.1
Membrane protease FtsH catalytic subunit; COGs: COG0465 ATP-dependent Zn protease; InterProIPR003593: IPR003959: IPR000642: IPR003960: IPR 005936; KEGG: dak:DaAHT2_0902 ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase central domain protein; PRIAM: Microtubule-severing ATPase; SMART: AAA ATPase; SPTR: ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH.
   
 0.641
ADW17097.1
GrpE protein; COGs: COG0576 Molecular chaperone GrpE (heat shock protein); InterPro IPR000740; KEGG: dak:DaAHT2_0057 GrpE protein; PFAM: GrpE protein; SPTR: Protein grpE; PFAM: GrpE.
  
  
 0.564
secY
Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.533
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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