Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW16264.1Radical SAM domain protein; COGs: COG1243 Histone acetyltransferase; InterPro IPR006638: IPR007197; KEGG: dps:DP1246 hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; PFAM: Radical SAM superfamily. (335 aa)    
Predicted Functional Partners:
rnc
RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
    0.790
ADW16265.1
COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR017871: IPR003439: IPR003593; KEGG: dak:DaAHT2_1049 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter.
  
   0.601
ADW17119.1
COGs: COG0101 Pseudouridylate synthase; InterPro IPR001406: IPR020097; KEGG: dak:DaAHT2_0355 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; SPTR: tRNA pseudouridine synthase A; TIGRFAM: tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I.
   
 
 0.574
ADW17154.1
COGs: COG0030 Dimethyladenosine transferase (rRNA methylation); InterPro IPR020598: IPR001737: IPR011530: IPR020596; KEGG: dak:DaAHT2_0616 dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; SMART: Ribosomal RNA adenine methylase transferase-like; SPTR: Dimethyladenosine transferase; TIGRFAM: dimethyladenosine transferase; PFAM: Ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase.
  
  
 0.565
ADW17204.1
tRNA(Ile)-lysidine synthetase; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063: IPR012795; KEGG: dps:DP2932 cell cycle protein MesJ; PFAM: PP-loop domain protein; SPTR: tRNA(Ile)-lysidine synthase; TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop family; TIGRFAM: tRNA(Ile)-lysidine synthetase, N-terminal domain.
  
 
 0.556
ADW17957.1
COGs: COG0009 Putative translation factor (SUA5); InterPro IPR004388: IPR006070; KEGG: dak:DaAHT2_1346 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Sua5/YciO/YrdC/YwlC family protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein.
 
   0.475
ADW17125.1
PP-loop domain protein; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR012089: IPR011063: IPR002362; KEGG: dps:DP1330 hypothetical protein; PFAM: PP-loop domain protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: PP-loop family.
   
 
 0.471
ADW18527.1
Protein of unknown function DUF2168; COGs: COG4752 conserved hypothetical protein; InterPro IPR019230; KEGG: dps:DP2804 hypothetical protein; PFAM: Protein of unknown function DUF2168; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2168).
  
     0.443
ADW18242.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR006140: IPR000594; KEGG: gur:Gura_1193 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family.
  
 
 0.439
ADW18668.1
Protein of unknown function Met10; COGs: COG2520 methyltransferase; InterPro IPR003402; KEGG: dps:DP0629 hypothetical protein; PFAM: protein of unknown function Met10; SPTR: Putative uncharacterized protein; PFAM: Met-10+ like-protein.
  
  
 0.424
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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