STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADW16416.1Nuclease (SNase domain-containing protein); COGs: COG1525 Micrococcal nuclease (thermonuclease) homologs; InterPro IPR002071: IPR006021; KEGG: dma:DMR_41750 putative nuclease; PFAM: nuclease (SNase domain-containing protein); SMART: nuclease (SNase domain-containing protein); SPTR: Putative nuclease; PFAM: Staphylococcal nuclease homologue. (220 aa)    
Predicted Functional Partners:
ADW18470.1
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477: IPR004797; KEGG: dps:DP1704 ComE operon protein 3; PFAM: ComEC/Rec2-related protein; SPTR: Related to ComE operon protein 3; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
     
 0.547
ADW18154.1
COGs: COG0117 Pyrimidine deaminase; InterProIPR016192: IPR004794: IPR011549: IPR002125: IPR 002734; KEGG: dak:DaAHT2_1279 riboflavin biosynthesis protein RibD; PFAM: bifunctional deaminase-reductase domain protein; CMP/dCMP deaminase zinc-binding; SPTR: Riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD.
  
  
 0.506
ADW19366.1
Competence/damage-inducible protein cinA; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453: IPR008136: IPR008135; KEGG: dak:DaAHT2_1904 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain.
     
 0.503
ADW17077.1
methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048: IPR001497; KEGG: scb:SCAB_17781 putative methylated-DNA-protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SPTR: Methylated-DNA/protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase.
  
  
 0.487
ADW18775.1
Exodeoxyribonuclease III Xth; COGs: COG0708 Exonuclease III; InterProIPR003265: IPR000097: IPR004808: IPR020847: IPR 020848: IPR004036: IPR003651: IPR005135; KEGG: dak:DaAHT2_1503 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; HhH-GPD family protein; iron-sulfur cluster loop; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD family protein; SPTR: Exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; HhH-GPD superfamily base excision DNA repair protein; H [...]
  
  
 0.487
ADW18354.1
Nuclease (SNase domain-containing protein); COGs: COG1525 Micrococcal nuclease (thermonuclease) homologs; InterPro IPR006021; KEGG: dma:DMR_41750 putative nuclease; PFAM: nuclease (SNase domain-containing protein); SMART: nuclease (SNase domain-containing protein); SPTR: Putative nuclease; PFAM: Staphylococcal nuclease homologue.
 
   
0.474
ADW18305.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: geo:Geob_0641 TPR repeat-containing protein; PFAM: glycosyl transferase group 1; SPTR: TPR repeat-containing protein; PFAM: Glycosyl transferases group 1.
 
 
 0.451
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
     
 0.446
ADW19194.1
Nuclease (SNase domain-containing protein); COGs: COG1525 Micrococcal nuclease (thermonuclease) homologs; InterPro IPR006021; KEGG: dal:Dalk_0541 nuclease (SNase domain protein); PFAM: nuclease (SNase domain-containing protein); SMART: nuclease (SNase domain-containing protein); SPTR: Nuclease (SNase domain protein); PFAM: Staphylococcal nuclease homologue.
  
    0.406
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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