Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW16435.1Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: paa:Paes_2294 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family. (126 aa)    
Predicted Functional Partners:
ADW16432.1
ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: dds:Ddes_1010 ABC-3 protein; PFAM: ABC-3 protein; SPTR: ABC-3 protein; PFAM: ABC 3 transport family.
 
  
 0.767
ADW16434.1
Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: dds:Ddes_1008 periplasmic solute binding protein; PFAM: periplasmic solute binding protein; SPTR: Periplasmic solute binding protein; PFAM: Periplasmic solute binding protein family.
 
  
 0.725
ADW19440.1
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: sfu:Sfum_3251 ferric uptake regulator family protein; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family.
  
     0.702
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.691
ADW19439.1
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COGs: COG0450 Peroxiredoxin; InterPro IPR000866: IPR019479: IPR017936; KEGG: gsu:GSU3246 thioredoxin peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; SPTR: Thioredoxin peroxidase; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family.
  
  
 0.664
ADW16433.1
ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: dds:Ddes_1009 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Putative uncharacterized protein; PFAM: ABC transporter.
 
     0.603
ADW18872.1
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: ppd:Ppro_1966 ferric uptake regulator family protein; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family.
  
     0.518
ADW16437.1
ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: dat:HRM2_23660 ABC-type transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC-type transporter, ATP-binding protein; PFAM: ABC transporter.
  
    0.514
ADW17621.1
Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: dak:DaAHT2_0358 iron (metal) dependent repressor, DtxR family; PFAM: iron dependent repressor; SMART: iron dependent repressor; SPTR: Iron (Metal) dependent repressor, DtxR family; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.
  
  
 0.493
ADW16436.1
Lipolytic protein G-D-S-L family; COGs: COG2755 Lysophospholipase L1 and related esterase; InterPro IPR008265: IPR001087; KEGG: dat:HRM2_23650 putative lipase/hydrolase; PFAM: lipolytic protein G-D-S-L family; SPTR: Putative lipase/hydrolase; PFAM: GDSL-like Lipase/Acylhydrolase.
       0.491
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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