Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ADW16447.1KEGG: vap:Vapar_2243 hypothetical protein; SPTR: Putative uncharacterized protein. (183 aa)    
Predicted Functional Partners:
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
  
  
 0.890
ADW18043.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterProIPR020845: IPR009081: IPR006163: IPR000873: IPR 002123; KEGG: ppr:PBPRB0014 acyltransferase family protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: Hypothetical acyltransferase family protein; PFAM: Phosphopantetheine attachment site; Acyltransferase; AMP-binding enzyme; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
   
 
 0.881
secY
Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
 
 0.854
ADW16952.1
Preprotein translocase, SecE subunit; InterPro IPR001901: IPR005807; KEGG: dps:DP1111 preprotein translocase SecE subunit (partial length); PFAM: protein secE/sec61-gamma protein; SPTR: Related to preprotein translocase secE subunit (Partial length); TIGRFAM: preprotein translocase, SecE subunit; manually curated; PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial.
    
 
 0.829
ADW19276.1
COGs: COG1314 Preprotein translocase subunit SecG; InterPro IPR004692; KEGG: dak:DaAHT2_0038 preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; SPTR: Preprotein translocase, SecG subunit; TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit.
   
 
 0.825
ADW19288.1
Protein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
   
 
 0.825
ADW17704.1
COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: dma:DMR_08520 alkaline phosphatase precursor; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; PFAM: Alkaline phosphatase.
    
 
 0.777
ADW16446.1
KEGG: pfd:PFDG_00166 predicted protein; SPTR: Phenylacetyl-CoA ligase.
       0.773
ADW16967.1
COGs: COG0089 Ribosomal protein L23; InterPro IPR013025; KEGG: dps:DP1126 50S ribosomal protein L23; PFAM: Ribosomal protein L25/L23; SPTR: 50S ribosomal protein L23; PFAM: Ribosomal protein L23.
   
 
 0.756
nifJ
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...]
  
    0.740
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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