STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16474.1COGs: COG0169 Shikimate 5-dehydrogenase; InterPro IPR011342: IPR013708: IPR006151; KEGG: dak:DaAHT2_0009 shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; SPTR: Shikimate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase. (278 aa)    
Predicted Functional Partners:
ADW16475.1
COGs: COG0710 3-dehydroquinate dehydratase; InterPro IPR001381; KEGG: dps:DP3013 3-dehydroquinate dehydratase; PFAM: dehydroquinase class I; PRIAM: 3-dehydroquinate dehydratase; SPTR: 3-dehydroquinate dehydratase; TIGRFAM: 3-dehydroquinate dehydratase, type I; PFAM: Type I 3-dehydroquinase; TIGRFAM: 3-dehydroquinate dehydratase, type I.
  
 0.999
ADW16473.1
3-phosphoshikimate 1-carboxyvinyltransferase; COGs: COG0128 5-enolpyruvylshikimate-3-phosphate synthase; InterPro IPR001986: IPR006264: IPR016228; KEGG: dak:DaAHT2_0008 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); SPTR: 3-phosphoshikimate 1-carboxyvinyltransferase; TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase.
  
 0.998
ADW19107.1
COGs: COG0703 Shikimate kinase; InterPro IPR000623; KEGG: dak:DaAHT2_2092 shikimate kinase; PFAM: shikimate kinase; PRIAM: Shikimate kinase; SPTR: Shikimate kinase; PFAM: Shikimate kinase.
 
 0.998
ADW17537.1
COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR016037: IPR016303: IPR002658; KEGG: dak:DaAHT2_0294 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase.
  
 0.985
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 0.945
ADW17294.1
COGs: COG0703 Shikimate kinase; InterPro IPR000623; KEGG: glo:Glov_3097 shikimate kinase; PFAM: shikimate kinase; SPTR: Shikimate kinase; PFAM: Shikimate kinase.
 
 
 0.939
ADW17259.1
COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; InterPro IPR004820: IPR005248: IPR004821; KEGG: dak:DaAHT2_1154 nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Nicotinate (Nicotinamide) nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain.
  
  
 0.862
ADW16476.1
Dihydroorotate oxidase B, catalytic subunit; COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR001295: IPR012135: IPR005720; KEGG: dps:DP3015 dihydroorotate dehydrogenase, catalytic subunit; PFAM: dihydroorotate oxidase; SPTR: Probable dihydroorotate dehydrogenase, catalytic subunit; TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein.
     
 0.830
ADW16477.1
Oxidoreductase FAD/NAD(P)-binding domain protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterProIPR017927: IPR012165: IPR008333: IPR001433: IPR 019480; KEGG: dps:DP3016 dihydroorotate dehydrogenase, electron transfer subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Related to dihydroorotate dehydrogenase, electron transfer subunit; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur [...]
       0.800
ADW17567.1
COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: dak:DaAHT2_0450 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase.
 
 0.784
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.