Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW16488.1Hypothetical protein; COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: dak:DaAHT2_2295 hypothetical protein; SPTR: Putative uncharacterized protein. (307 aa)    
Predicted Functional Partners:
ADW16489.1
COGs: COG1639 signal transduction protein; InterPro IPR006675: IPR013976; KEGG: dps:DP0004 hypothetical protein; PFAM: Metal-dependent hydrolase HDOD; SPTR: Putative uncharacterized protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG.
 
     0.815
ADW18966.1
Adenylate/guanylate cyclase with GAF sensor(s); COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054: IPR003018; KEGG: dal:Dalk_4220 adenylate/guanylate cyclase with GAF sensor(s); PFAM: GAF domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: GAF domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase with GAF sensor(S); manually curated; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain.
 
     0.747
ADW18489.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: dol:Dole_2199 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
 
     0.711
ADW18355.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595: IPR002373: IPR018488; KEGG: dal:Dalk_3876 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
 
     0.622
ADW16487.1
Selenium metabolism protein YedF; InterPro IPR019870: IPR001455; KEGG: pca:Pcar_0303 redox protein, regulator of disulfide bond formation; PFAM: SirA-like domain-containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA-like protein; DsrE/DsrF-like family; TIGRFAM: selenium metabolism protein YedF.
       0.608
ADW19181.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: dol:Dole_2199 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
 
     0.582
ADW16492.1
KEGG: dak:DaAHT2_2292 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.549
ADW16486.1
COGs: COG0793 Periplasmic protease; InterPro IPR001478: IPR005151: IPR004447; KEGG: dps:DP3077 periplasmic tail-specific proteinase; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; PRIAM: C-terminal processing peptidase; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: Probable periplasmic tail-specific proteinase; TIGRFAM: carboxyl-terminal protease; PFAM: C-terminal domain of tail specific protease (DUF3340); Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc).
       0.456
ADW18683.1
Multi-sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR004358: IPR003661: IPR003594: IPR005467: IPR 001901: IPR007890: IPR013656; KEGG: pfs:PFLU0007 putative two-component system, sensor kinase; PFAM: CHASE2 domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: CHASE domain/sensor histidine kinase; PFAM: CHASE2 domain; Histidine kinase-, DNA gyrase B-, and HSP90-like AT [...]
  
  
 0.453
ADW16491.1
COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR011858: IPR006062; KEGG: dak:DaAHT2_2293 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; SPTR: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, eukaryotic; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, eukaryotic type.
       0.447
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.