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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16492.1KEGG: dak:DaAHT2_2292 hypothetical protein; SPTR: Putative uncharacterized protein. (231 aa)    
Predicted Functional Partners:
ADW16934.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013655: IPR013656: IPR013767: IPR003661: IPR 003594: IPR004358: IPR000014: IPR001610: IPR005467: IPR000700; KEGG: mba:Mbar_A0404 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: PAS fold family; TI [...]
   
 
 0.887
ADW17844.1
COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR000014: IPR001610: IPR003661: IPR003594: IPR 013655: IPR013656: IPR004358: IPR005467: IPR000700; KEGG: azo:azo2457 putative sensory box histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Multi-sensor signal transduction histidine kinas [...]
   
 
 0.887
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
 
     0.873
ADW17808.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR004358: IPR 005467; KEGG: pca:Pcar_0361 two component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: Two component sensor histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   
 
 0.845
ADW18958.1
Histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR005467: IPR003594; KEGG: dak:DaAHT2_0503 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
   
 
 0.845
ADW18765.1
KEGG: dps:DP3093 hypothetical protein; SPTR: Putative uncharacterized protein.
 
    
 0.750
ADW17139.1
KEGG: dak:DaAHT2_0340 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.732
ADW18849.1
Peptidase M48 Ste24p; InterPro IPR019734: IPR013026: IPR001915; KEGG: dps:DP0525 hypothetical protein; PFAM: peptidase M48 Ste24p; SPTR: Putative uncharacterized protein; PFAM: Peptidase family M48.
  
     0.677
ADW16234.1
KEGG: dak:DaAHT2_1493 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.660
ADW18130.1
Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: dps:DP1477 heme biosynthesis protein; PFAM: Radical SAM domain protein; SPTR: Related to heme biosynthesis protein; PFAM: Radical SAM superfamily.
  
     0.660
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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