Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW16495.1Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dal:Dalk_2439 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family. (439 aa)    
Predicted Functional Partners:
ADW17066.1
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dak:DaAHT2_0644 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
  
  
 
0.914
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
  0.909
ADW16217.1
Hypothetical protein; COGs: COG0421 Spermidine synthase; KEGG: mca:MCA1034 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Spermine/spermidine synthase.
   
  0.906
ADW18905.1
Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: dak:DaAHT2_2303 protein of unknown function DUF152; PFAM: protein of unknown function DUF152; SPTR: Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family.
     
  0.900
ADW16496.1
GTP-binding protein YchF; COGs: COG0012 GTPase probable translation factor; InterPro IPR004396: IPR006073: IPR002917: IPR013029; KEGG: dps:DP0782 GTP-dependent nucleic acid-binding protein EngD; PFAM: protein of unknown function DUF933; GTP-binding protein HSR1-related; SPTR: Probable GTP-binding protein (YchF); TIGRFAM: GTP-binding protein YchF; PFAM: GTPase of unknown function; Protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF.
  
    0.536
ADW19076.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
  
  
 0.531
ADW17065.1
Inosine guanosine and xanthosine phosphorylase family; COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR000845: IPR011268; KEGG: dak:DaAHT2_0643 purine nucleoside phosphorylase I, inosine and guanosine-specific; PFAM: purine or other phosphorylase family 1; SPTR: Inosine guanosine and xanthosine phosphorylase:Purine nucleoside phosphorylase I, inosine and guanosine-specific; TIGRFAM: inosine guanosine and xanthosine phosphorylase family; PFAM: Phosphorylase superfamily; TIGRFAM: inosine guanosine and xanthosine phosphorylase family.
  
 0.485
ADW16498.1
COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR001270: IPR004622: IPR003593; KEGG: dak:DaAHT2_1885 DNA polymerase III, delta prime subunit; SMART: AAA ATPase; SPTR: DNA polymerase III delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit.
   
   0.431
ADW16497.1
Metal dependent phosphohydrolase; COGs: COG3481 HD-superfamily hydrolase; InterPro IPR006675: IPR004365: IPR006674: IPR003607; KEGG: dak:DaAHT2_1884 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; nucleic acid binding OB-fold tRNA/helicase-type; SMART: metal-dependent phosphohydrolase HD region; SPTR: HDIG; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; OB-fold nucleic acid binding domain; TIGRFAM: uncharacterized domain HDIG.
       0.400
ADW16499.1
PSP1 domain protein; COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557: IPR019742; KEGG: dps:DP0785 hypothetical protein; PFAM: PSP1 domain protein; SPTR: Putative uncharacterized protein; PFAM: PSP1 C-terminal conserved region.
       0.400
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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