STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htpXHeat shock protein; COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR001915; KEGG: ppd:Ppro_3243 peptidase M48, Ste24p; PFAM: peptidase M48 Ste24p; SPTR: HtpX-2 peptidase. Metallo peptidase. MEROPS family M48B; PFAM: Peptidase family M48; Belongs to the peptidase M48B family. (278 aa)    
Predicted Functional Partners:
ADW17097.1
GrpE protein; COGs: COG0576 Molecular chaperone GrpE (heat shock protein); InterPro IPR000740; KEGG: dak:DaAHT2_0057 GrpE protein; PFAM: GrpE protein; SPTR: Protein grpE; PFAM: GrpE.
  
  
 0.624
ADW18436.1
Protein of unknown function DUF533; COGs: COG2979 conserved hypothetical protein; InterPro IPR007486; KEGG: ppd:Ppro_3114 hypothetical protein; PFAM: protein of unknown function DUF533; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF533).
   
    0.616
ADW18971.1
Protein of unknown function UPF0005; COGs: COG0670 Integral membrane protein interacts with FtsH; InterPro IPR006214; KEGG: dps:DP1672 hypothetical protein; PFAM: protein of unknown function UPF0005; SPTR: Conserved hypothetical membrane protein, probably cold-shock inducible; PFAM: Uncharacterised protein family UPF0005.
  
  
 0.563
ADW18377.1
Surface presentation of antigens (SPOA) protein; COGs: COG1868 Flagellar motor switch protein; InterPro IPR001689: IPR001543; KEGG: drt:Dret_0581 flagellar motor switch protein FliM; PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; SPTR: Flagellar motor switch protein FliM; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.
    
   0.516
ADW18078.1
COGs: COG0225 Peptide methionine sulfoxide reductase; InterPro IPR002569: IPR002579; KEGG: tau:Tola_0999 methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; Methionine sulfoxide reductase A; PRIAM: Peptide-methionine (S)-S-oxide reductase., Peptide-methionine (R)-S-oxide reductase; SPTR: Methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; peptide methionine sulfoxide reductase; PFAM: SelR domain; Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; methionine-R-sulfoxide reductase.
  
  
 0.486
ADW18122.1
COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterProIPR003095: IPR012724: IPR018253: IPR001623: IPR 001305: IPR002939; KEGG: dps:DP1482 chaperone protein DnaJ; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; DnaJ central domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Chaperone protein dnaJ; TIGRFAM: chaperone protein DnaJ; PFAM: DnaJ domain; DnaJ central domain (4 repeats); DnaJ C terminal region; TIGRFAM: chaperone protein DnaJ.
  
 
 0.481
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 
 0.470
groS
Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
  
 0.462
ADW16505.1
ThiJ/PfpI domain-containing protein; COGs: COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis; InterPro IPR002818; KEGG: dps:DP0859 isoprenoid biosynthesis protein with amidotransferase-like domain; PFAM: ThiJ/PfpI domain-containing protein; SPTR: Putative uncharacterized protein; PFAM: DJ-1/PfpI family.
       0.453
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
  
 0.451
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.