STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16545.1COGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); InterPro IPR002891: IPR002650; KEGG: drt:Dret_2034 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; PFAM: ATP-sulfurylase; adenylylsulfate kinase; PRIAM: Sulfate adenylyltransferase., Adenylyl-sulfate kinase; SPTR: Adenylylsulfate kinase; TIGRFAM: adenylylsulfate kinase; PFAM: ATP-sulfurylase; Adenylylsulphate kinase; TIGRFAM: adenylylsulfate kinase (apsK); ATP sulphurylase. (569 aa)    
Predicted Functional Partners:
cobA
COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366: IPR003043: IPR000878: IPR003754; KEGG: dps:DP1734 uroporphyrinogen III synthase/methyltransferase (HemD+CobA); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Probable uroporphyrinogen III synthase/methyltransferase (HemD+CobA); TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
  
  
 0.989
sat
COGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); InterPro IPR002650; KEGG: dps:DP1472 sulfate adenylyltransferase; PFAM: ATP-sulfurylase; PRIAM: Sulfate adenylyltransferase; SPTR: Probable sulfate adenylyltransferase; TIGRFAM: sulfate adenylyltransferase; PFAM: ATP-sulfurylase; TIGRFAM: ATP sulphurylase.
 
 
0.988
ADW18402.1
COGs: COG0529 Adenylylsulfate kinase and related kinase; InterPro IPR002891; KEGG: alv:Alvin_1127 adenylylsulfate kinase; PFAM: adenylylsulfate kinase; PRIAM: Adenylyl-sulfate kinase; SPTR: Adenylylsulfate kinase; TIGRFAM: adenylylsulfate kinase; PFAM: Adenylylsulphate kinase; TIGRFAM: adenylylsulfate kinase (apsK).
 
 
0.986
aprA
Dissimilatory adenylylsulfate reductase alpha subunit precursor; COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR006076: IPR011803; KEGG: dak:DaAHT2_1471 adenylylsulfate reductase, alpha subunit; PFAM: FAD dependent oxidoreductase; SPTR: AprA; TIGRFAM: adenylylsulfate reductase, alpha subunit; PFAM: domain; FAD binding domain; TIGRFAM: adenosine phosphosulphate reductase, alpha subunit.
 
 
 0.979
aprB
InterPro IPR011802: IPR017900: IPR017896; KEGG: dak:DaAHT2_1472 adenylylsulfate reductase, beta subunit; SPTR: Adenylylsulfate reductase, beta subunit; TIGRFAM: adenylylsulfate reductase, beta subunit; PFAM: Adenosine-5'-phosphosulfate reductase beta subunit; TIGRFAM: adenosine phosphosulphate reductase, beta subunit.
  
 
 0.972
ADW18784.1
Histidine triad (HIT) protein; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: dps:DP0841 hypothetical protein; PFAM: histidine triad (HIT) protein; SPTR: Putative uncharacterized protein; PFAM: HIT domain.
    
 0.902
ADW19050.1
Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667: IPR003156; KEGG: dak:DaAHT2_1878 phosphoesterase RecJ domain protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ-like:Phosphoesterase, DHHA1; PFAM: DHH family; DHHA1 domain.
    
  0.900
ADW18745.1
COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367; KEGG: dak:DaAHT2_2550 siroheme synthase; SPTR: Siroheme synthase; TIGRFAM: siroheme synthase; TIGRFAM: siroheme synthase, N-terminal domain.
  
  
 0.891
ADW17109.1
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140: IPR000169; KEGG: dps:DP1709 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Related to D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
   
  
 0.865
dsrA
COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterPro IPR017896: IPR006067: IPR011806; KEGG: dps:DP0797 dissimilatory sulfite reductase, alpha subunit (DsrA); PFAM: nitrite and sulphite reductase 4Fe-4S region; PRIAM: Hydrogensulfite reductase; SPTR: Dissimilatory sulfite reductase subunit A; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit.
  
  
 0.758
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.