node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADW16431.1 | ADW16562.1 | Despr_0244 | Despr_0380 | ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain. | COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase. | 0.919 |
ADW16431.1 | ADW16563.1 | Despr_0244 | Despr_0381 | ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.920 |
ADW16431.1 | ADW16615.1 | Despr_0244 | Despr_0434 | ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain. | COGs: COG0280 Phosphotransacetylase; InterPro IPR016475: IPR004614: IPR010766: IPR002505; KEGG: sdl:Sdel_1045 phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; DRTGG domain protein; PRIAM: Phosphate acetyltransferase; SPTR: Phosphate acetyltransferase; TIGRFAM: phosphate acetyltransferase; PFAM: DRTGG domain; Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase. | 0.920 |
ADW16431.1 | ADW17373.1 | Despr_0244 | Despr_1204 | ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain. | COGs: COG2225 Malate synthase; InterPro IPR011076; KEGG: sti:Sthe_2906 malate synthase A; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: Malate synthase; PFAM: Malate synthase; TIGRFAM: malate synthase A. | 0.900 |
ADW16431.1 | ADW17656.1 | Despr_0244 | Despr_1502 | ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain. | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873: IPR020845; KEGG: gur:Gura_1608 acetyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. | 0.913 |
ADW16431.1 | ADW18411.1 | Despr_0244 | Despr_2267 | ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain. | CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterProIPR011761: IPR003781: IPR005811: IPR013650: IPR 018087; KEGG: dak:DaAHT2_1111 CoA-binding domain protein; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain. | 0.921 |
ADW16431.1 | ADW18758.1 | Despr_0244 | Despr_2622 | ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain. | COGs: COG1254 Acylphosphatase; InterPro IPR020456: IPR001792: IPR017968; KEGG: sfu:Sfum_1427 acylphosphatase; PFAM: acylphosphatase; SPTR: Acylphosphatase; PFAM: Acylphosphatase. | 0.900 |
ADW16431.1 | acs | Despr_0244 | Despr_2672 | ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.913 |
ADW16431.1 | nifJ | Despr_0244 | Despr_2558 | ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...] | 0.956 |
ADW16562.1 | ADW16431.1 | Despr_0380 | Despr_0244 | COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase. | ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain. | 0.919 |
ADW16562.1 | ADW16563.1 | Despr_0380 | Despr_0381 | COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.999 |
ADW16562.1 | ADW16565.1 | Despr_0380 | Despr_0383 | COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase. | Protein of unknown function DUF162; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: ppd:Ppro_3136 hypothetical protein; PFAM: protein of unknown function DUF162; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised ACR, YkgG family COG1556. | 0.892 |
ADW16562.1 | ADW16615.1 | Despr_0380 | Despr_0434 | COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase. | COGs: COG0280 Phosphotransacetylase; InterPro IPR016475: IPR004614: IPR010766: IPR002505; KEGG: sdl:Sdel_1045 phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; DRTGG domain protein; PRIAM: Phosphate acetyltransferase; SPTR: Phosphate acetyltransferase; TIGRFAM: phosphate acetyltransferase; PFAM: DRTGG domain; Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase. | 0.999 |
ADW16562.1 | ADW17373.1 | Despr_0380 | Despr_1204 | COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase. | COGs: COG2225 Malate synthase; InterPro IPR011076; KEGG: sti:Sthe_2906 malate synthase A; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: Malate synthase; PFAM: Malate synthase; TIGRFAM: malate synthase A. | 0.859 |
ADW16562.1 | ADW17656.1 | Despr_0380 | Despr_1502 | COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase. | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873: IPR020845; KEGG: gur:Gura_1608 acetyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. | 0.968 |
ADW16562.1 | ADW18411.1 | Despr_0380 | Despr_2267 | COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase. | CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterProIPR011761: IPR003781: IPR005811: IPR013650: IPR 018087; KEGG: dak:DaAHT2_1111 CoA-binding domain protein; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain. | 0.919 |
ADW16562.1 | ADW18758.1 | Despr_0380 | Despr_2622 | COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase. | COGs: COG1254 Acylphosphatase; InterPro IPR020456: IPR001792: IPR017968; KEGG: sfu:Sfum_1427 acylphosphatase; PFAM: acylphosphatase; SPTR: Acylphosphatase; PFAM: Acylphosphatase. | 0.918 |
ADW16562.1 | acs | Despr_0380 | Despr_2672 | COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.968 |
ADW16562.1 | nifJ | Despr_0380 | Despr_2558 | COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...] | 0.843 |
ADW16563.1 | ADW16431.1 | Despr_0381 | Despr_0244 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain. | 0.920 |