Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW16566.1COGs: COG1620 L-lactate permease; InterPro IPR003804; KEGG: gur:Gura_2200 L-lactate transport; PFAM: L-lactate permease; SPTR: L-lactate transport; TIGRFAM: L-lactate transport; PFAM: L-lactate permease; TIGRFAM: L-lactate transport. (649 aa)    
Predicted Functional Partners:
ADW16891.1
COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262: IPR012133; KEGG: chy:CHY_1319 FMN-dependent family dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: Dehydrogenase, FMN-dependent family; PFAM: FMN-dependent dehydrogenase.
  
 0.887
ADW16564.1
Protein of unknown function DUF162; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR017896: IPR003741: IPR004017: IPR017900; KEGG: gur:Gura_0152 hypothetical protein; PFAM: protein of unknown function DUF162; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain; Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein.
 
   
 0.873
ADW16565.1
Protein of unknown function DUF162; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: ppd:Ppro_3136 hypothetical protein; PFAM: protein of unknown function DUF162; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised ACR, YkgG family COG1556.
 
   
 0.850
ADW17605.1
L-lactate permease, putative; COGs: COG1620 L-lactate permease; KEGG: gsu:GSU0226 L-lactate permease, putative; SPTR: L-lactate permease; PFAM: L-lactate permease.
  
     0.679
ADW16569.1
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR012257: IPR017896: IPR004017: IPR017900; KEGG: ppd:Ppro_2541 hypothetical protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain.
 
  
 0.673
ADW16567.1
Transcriptional regulator, GntR family; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: ppd:Ppro_2670 GntR domain-containing protein; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
  
 0.657
ADW16562.1
COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase.
     
 0.623
ADW18259.1
D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR017900: IPR017896: IPR016166: IPR006094: IPR 004113; KEGG: dvl:Dvul_2725 D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase domain protein; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: D-lactate dehydrogenase (Cytochrome); PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain.
 
  
 0.607
ADW16563.1
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.603
ADW16568.1
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR016166: IPR006094: IPR004113: IPR020904: IPR 018130; KEGG: ppd:Ppro_2540 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase domain protein; SPTR: FAD linked oxidase domain protein; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
 
  
 0.535
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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