STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16602.1Sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR000253: IPR002078: IPR020441: IPR003018: IPR 002197: IPR003593; KEGG: psl:Psta_3595 transcriptional regulator, NifA subfamily, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; Forkhead-associated protein; GAF domain protein; helix-turn-helix Fis-type; SMART: Forkhead-associated protein; GAF domain protein; AAA ATPase; SPTR: Transcriptional regulator, NifA subfamily, Fis Family; PFAM: GAF domain; Bacter [...] (627 aa)    
Predicted Functional Partners:
ADW17130.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR004358: IPR005467: IPR003660: IPR003594; KEGG: dba:Dbac_0214 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SPTR: Histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   
 
 0.962
ADW19079.1
Hypothetical protein; InterPro IPR000608: IPR019734; KEGG: dps:DP0803 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 0.939
fliN
COGs: COG1886 Flagellar motor switch/type III secretory pathway protein; InterPro IPR001172: IPR001543: IPR012826; KEGG: dps:DP2669 flagellar motor switch protein (FliN); PFAM: surface presentation of antigens (SPOA) protein; SPTR: Probable flagellar motor switch protein (FliN); TIGRFAM: flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); TIGRFAM: flagellar motor switch protein FliN.
  
 
 0.934
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
   
 
 0.907
ADW18367.1
Flagellar assembly protein FliH/Type III secretion system HrpE; COGs: COG1317 Flagellar biosynthesis/type III secretory pathway protein; InterPro IPR018035; KEGG: pca:Pcar_1190 flagellar biosynthesis protein; PFAM: Flagellar assembly protein FliH/Type III secretion system HrpE; SPTR: Flagellar assembly protein FliH, putative; PFAM: Flagellar assembly protein FliH.
  
 
 0.904
ADW17348.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 000700: IPR008207: IPR001610: IPR003661: IPR003594: IPR013656:I PR013767; KEGG: alv:Alvin_2605 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator re [...]
  
 
 0.901
fliI
Type III secretion system ATPase, FliI/YscN; COGs: COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; InterPro IPR003593: IPR000194: IPR020003: IPR005714; KEGG: dps:DP2659 flagellum-specific ATP synthase (FliI); PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; SMART: AAA ATPase; SPTR: ATPase FliI/YscN; TIGRFAM: ATPase, FliI/YscN family; PFAM: ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family.
  
 
 0.894
ADW18652.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003018: IPR 003661: IPR003594: IPR001789: IPR008207: IPR005467: IPR000700:I PR013767: IPR013655: IPR013656; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain pro [...]
  
 
 0.887
ADW17653.1
Dihydrolipoyllysine-residue acetyltransferase; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089: IPR004167: IPR001078; KEGG: gur:Gura_1611 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; PRIAM: Dihydrolipoyllysine-residue acetyltransferase; SPTR: Catalytic domain of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehyd [...]
   
 
 0.871
ADW18305.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: geo:Geob_0641 TPR repeat-containing protein; PFAM: glycosyl transferase group 1; SPTR: TPR repeat-containing protein; PFAM: Glycosyl transferases group 1.
  
 
 0.852
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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