Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW16609.1FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterProIPR000253: IPR003439: IPR013525: IPR017871: IPR 003593; KEGG: cag:Cagg_0751 FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; PFAM: ABC transporter related; Forkhead-associated protein; ABC-2 type transporter; SMART: Forkhead-associated protein; AAA ATPase; SPTR: FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; PFAM: ABC transporter; FHA domain; ABC-2 type transporter. (871 aa)    
Predicted Functional Partners:
ADW16610.1
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000719: IPR017442: IPR017441: IPR008271: IPR 020635: IPR002290; KEGG: sro:Sros_7190 WD40 repeat-domain-containing protein-like protein; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: WD40 repeat-domain-containing protein-like protein; PFAM: Protein kinase domain.
 
 
 0.958
ADW17771.1
Protein of unknown function DUF181; COGs: COG1944 conserved hypothetical protein; InterPro IPR003776: IPR019734: IPR001440: IPR013026; KEGG: dps:DP1955 hypothetical protein; PFAM: protein of unknown function DUF181; Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: Putative uncharacterized protein; PFAM: YcaO-like family; Tetratricopeptide repeat; TIGRFAM: uncharacterized domain; bacteriocin biosynthesis docking scaffold, SagD family.
  
 
 0.895
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
   
 
 0.875
ADW17471.1
COGs: COG1277 ABC-type transport system involved in multi-copper enzyme maturation permease component; InterPro IPR019196; KEGG: nhl:Nhal_1154 ABC transporter, inner membrane protein; PFAM: ABC-type uncharacterised transport system; SPTR: ABC transporter, inner membrane protein; PFAM: ABC-type uncharacterized transport system.
 
 
 0.866
ADW17492.1
ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterProIPR003439: IPR000412: IPR013525: IPR003593: IPR 017871; KEGG: glo:Glov_3419 ABC transporter related; PFAM: ABC transporter related; ABC-2 type transporter; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter; ABC-2 type transporter.
  
  
 0.856
ADW17130.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR004358: IPR005467: IPR003660: IPR003594; KEGG: dba:Dbac_0214 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SPTR: Histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
 
 0.843
ADW19079.1
Hypothetical protein; InterPro IPR000608: IPR019734; KEGG: dps:DP0803 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 0.822
ADW17152.1
Abortive infection protein; InterPro IPR003675; KEGG: dat:HRM2_19830 hypothetical protein; PFAM: Abortive infection protein; SPTR: Putative uncharacterized protein; PFAM: CAAX amino terminal protease family; TIGRFAM: CAAX prenyl protease-related protein.
  
  
 0.799
ADW17128.1
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000719: IPR020635: IPR002290: IPR017442: IPR 017441: IPR008271; KEGG: dde:Dde_3468 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: Serine/threonine protein kinase; PFAM: Protein kinase domain; Protein of unknown function (DUF1566).
  
 
 0.798
ADW17300.1
Thiol-activated cytolysin; InterPro IPR001869; KEGG: ctc:CTC01888 tetanolysin O; PFAM: Thiol-activated cytolysin; SPTR: Tetanolysin O; PFAM: Thiol-activated cytolysin.
  
 
 0.798
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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