STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16613.1InterPro IPR011701; KEGG: pth:PTH_2046 major facilitator superfamily permease; PFAM: major facilitator superfamily MFS_1; SPTR: Permeases of the major facilitator superfamily; PFAM: Major Facilitator Superfamily. (453 aa)    
Predicted Functional Partners:
ADW16912.1
COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017: IPR017900: IPR017896; KEGG: geo:Geob_0246 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain.
  
  
 0.692
ADW16483.1
Putative sulfite reductase-associated electron transfer protein DsrM; COGs: COG2181 Nitrate reductase gamma subunit; InterPro IPR001412: IPR003816; KEGG: dps:DP3075 hypothetical protein; PFAM: Nitrate reductase gamma subunit; SPTR: Hypothetical membrane protein; PFAM: Nitrate reductase gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit.
  
  
 0.681
cobA
COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366: IPR003043: IPR000878: IPR003754; KEGG: dps:DP1734 uroporphyrinogen III synthase/methyltransferase (HemD+CobA); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Probable uroporphyrinogen III synthase/methyltransferase (HemD+CobA); TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
  
  
 0.580
ADW17753.1
NAD(P)-dependent iron-only hydrogenase catalytic subunit; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352: IPR001041: IPR019574: IPR004108: IPR 003149: IPR017896: IPR017900: IPR000283; KEGG: dma:DMR_07830 putative Fe hydrogenase; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Putative Fe hydrogenase; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulf [...]
  
  
 0.473
nifU
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
  
 0.442
ADW18940.1
Molybdopterin biosynthesis MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: dps:DP2875 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Similar to molybdenum cofactor biosynthesis protein; PFAM: MoaE protein.
  
  
 0.421
ADW18745.1
COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367; KEGG: dak:DaAHT2_2550 siroheme synthase; SPTR: Siroheme synthase; TIGRFAM: siroheme synthase; TIGRFAM: siroheme synthase, N-terminal domain.
 
  
 0.417
ADW18175.1
PAS sensor protein; InterProIPR000014: IPR000700: IPR003018: IPR013656: IPR 003661: IPR001610; KEGG: dat:HRM2_42110 GGDEF domain family protein; PFAM: GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: GAF domain protein; PAC repeat-containing protein; histidine kinase A domain protein; SPTR: GGDEF domain family protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.
     
 0.415
ADW17796.1
Major facilitator superfamily MFS_1; COGs: COG2271 Sugar phosphate permease; InterPro IPR011701: IPR005829; KEGG: dds:Ddes_1414 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily.
 
  
 0.409
ADW18966.1
Adenylate/guanylate cyclase with GAF sensor(s); COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054: IPR003018; KEGG: dal:Dalk_4220 adenylate/guanylate cyclase with GAF sensor(s); PFAM: GAF domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: GAF domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase with GAF sensor(S); manually curated; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain.
     
 0.407
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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