STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16619.1InterPro IPR017896: IPR017900; KEGG: gem:GM21_3090 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain. (95 aa)    
Predicted Functional Partners:
ADW16620.1
COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); KEGG: dba:Dbac_0376 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein)-like protein; SPTR: Putative uncharacterized protein; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit.
 
     0.949
nifJ
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...]
  
 
 0.737
aprA
Dissimilatory adenylylsulfate reductase alpha subunit precursor; COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR006076: IPR011803; KEGG: dak:DaAHT2_1471 adenylylsulfate reductase, alpha subunit; PFAM: FAD dependent oxidoreductase; SPTR: AprA; TIGRFAM: adenylylsulfate reductase, alpha subunit; PFAM: domain; FAD binding domain; TIGRFAM: adenosine phosphosulphate reductase, alpha subunit.
  
 
 0.706
ADW18491.1
COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953: IPR004112: IPR011280; KEGG: dps:DP2136 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase; SPTR: Probable succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup.
  
 
 0.706
ADW16618.1
Protein of unknown function DUF523; COGs: COG3272 conserved hypothetical protein; InterPro IPR007553: IPR013560; KEGG: sat:SYN_02271 putative cytoplasmic protein; PFAM: protein of unknown function DUF523; protein of unknown function DUF1722; SPTR: Hypothetical cytosolic protein; PFAM: Protein of unknown function (DUF523); Protein of unknown function (DUF1722).
       0.664
ADW16249.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752: IPR002880; KEGG: dat:HRM2_42780 PorA3; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: PorA3; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.
  
 
 0.551
ADW17753.1
NAD(P)-dependent iron-only hydrogenase catalytic subunit; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352: IPR001041: IPR019574: IPR004108: IPR 003149: IPR017896: IPR017900: IPR000283; KEGG: dma:DMR_07830 putative Fe hydrogenase; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Putative Fe hydrogenase; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulf [...]
     
 0.494
ADW17936.1
COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: mag:amb1113 Ni,Fe-hydrogenase maturation factor; PFAM: peptidase M52 hydrogen uptake protein; SPTR: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease.
  
     0.469
ADW16545.1
COGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); InterPro IPR002891: IPR002650; KEGG: drt:Dret_2034 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; PFAM: ATP-sulfurylase; adenylylsulfate kinase; PRIAM: Sulfate adenylyltransferase., Adenylyl-sulfate kinase; SPTR: Adenylylsulfate kinase; TIGRFAM: adenylylsulfate kinase; PFAM: ATP-sulfurylase; Adenylylsulphate kinase; TIGRFAM: adenylylsulfate kinase (apsK); ATP sulphurylase.
  
  
 0.416
ADW18441.1
Glutamate synthase (NADPH) GltB2 subunit; COGs: COG0069 Glutamate synthase domain 2; KEGG: dal:Dalk_0522 ferredoxin-dependent glutamate synthase; SPTR: Ferredoxin-dependent glutamate synthase; PFAM: Conserved region in glutamate synthase.
  
     0.400
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.