Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW16619.1InterPro IPR017896: IPR017900; KEGG: gem:GM21_3090 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain. (95 aa)    
Predicted Functional Partners:
ADW16620.1
COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); KEGG: dba:Dbac_0376 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein)-like protein; SPTR: Putative uncharacterized protein; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit.
 
     0.951
ADW17753.1
NAD(P)-dependent iron-only hydrogenase catalytic subunit; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352: IPR001041: IPR019574: IPR004108: IPR 003149: IPR017896: IPR017900: IPR000283; KEGG: dma:DMR_07830 putative Fe hydrogenase; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Putative Fe hydrogenase; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulf [...]
   
 
 0.937
nifJ
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...]
  
 
 0.744
ADW16618.1
Protein of unknown function DUF523; COGs: COG3272 conserved hypothetical protein; InterPro IPR007553: IPR013560; KEGG: sat:SYN_02271 putative cytoplasmic protein; PFAM: protein of unknown function DUF523; protein of unknown function DUF1722; SPTR: Hypothetical cytosolic protein; PFAM: Protein of unknown function (DUF523); Protein of unknown function (DUF1722).
       0.664
ADW16249.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752: IPR002880; KEGG: dat:HRM2_42780 PorA3; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: PorA3; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.
  
 
 0.546
ADW18215.1
NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR001949: IPR011538: IPR019554: IPR019575; KEGG: sus:Acid_5018 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 24 Kd [...]
   
 
 0.528
aprA
Dissimilatory adenylylsulfate reductase alpha subunit precursor; COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR006076: IPR011803; KEGG: dak:DaAHT2_1471 adenylylsulfate reductase, alpha subunit; PFAM: FAD dependent oxidoreductase; SPTR: AprA; TIGRFAM: adenylylsulfate reductase, alpha subunit; PFAM: domain; FAD binding domain; TIGRFAM: adenosine phosphosulphate reductase, alpha subunit.
  
 
 0.520
ADW18491.1
COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953: IPR004112: IPR011280; KEGG: dps:DP2136 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase; SPTR: Probable succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup.
  
 
 0.520
ADW17516.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR017896: IPR013027: IPR000103: IPR017900; KEGG: sfu:Sfum_0014 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain.
  
 
 0.496
ADW17787.1
FAD dependent oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR006076: IPR004017: IPR006058: IPR017900; KEGG: pth:PTH_0680 hypothetical protein; PFAM: FAD dependent oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain.
   
 
 0.486
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.