Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW16624.1Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR004838; KEGG: dat:HRM2_00100 putative aminotransferase; PFAM: aminotransferase class I and II; SPTR: Putative aminotransferase; PFAM: Aminotransferase class I and II. (415 aa)    
Predicted Functional Partners:
ADW16625.1
ABC transporter related protein; COGs: COG4172 ABC-type uncharacterized transport system duplicated ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: avn:Avin_29680 ABC transporter, ATP binding component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: phosphonate C-P lyase system protein PhnK.
       0.508
ADW16626.1
COGs: COG1416 conserved hypothetical protein; KEGG: dde:Dde_2602 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: DsrE/DsrF-like family.
       0.508
ADW19022.1
Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: cja:CJA_3147 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase large chain; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.497
ADW16623.1
COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit; PFAM: amino acid-binding ACT domain protein; SPTR: Amino acid-binding ACT domain protein; PFAM: ACT domain; TIGRFAM: acetolactate synthase, small subunit.
  
   0.483
ADW18433.1
COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR000183: IPR002986; KEGG: rce:RC1_1016 diaminopimelate decarboxylase, putative; PFAM: Orn/DAP/Arg decarboxylase 2; PRIAM: Diaminopimelate decarboxylase; SPTR: Diaminopimelate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain.
 
  
 0.476
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
  
 
 0.425
ADW16622.1
Acetolactate synthase, large subunit; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterProIPR012846: IPR012001: IPR012000: IPR011766: IPR 000399; KEGG: dde:Dde_0398 acetolactate synthase catalytic subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; SPTR: Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-termi [...]
  
 
 0.413
ADW16702.1
COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220: IPR005263: IPR020624: IPR020625; KEGG: dps:DP0432 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; PRIAM: Dihydrodipicolinate synthase; SPTR: Dihydrodipicolinate synthase; TIGRFAM: dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase.
 
   
 0.402
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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