STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16647.1Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: dak:DaAHT2_2664 transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain. (306 aa)    
Predicted Functional Partners:
ADW16487.1
Selenium metabolism protein YedF; InterPro IPR019870: IPR001455; KEGG: pca:Pcar_0303 redox protein, regulator of disulfide bond formation; PFAM: SirA-like domain-containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA-like protein; DsrE/DsrF-like family; TIGRFAM: selenium metabolism protein YedF.
  
   
 0.503
ADW19022.1
Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: cja:CJA_3147 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase large chain; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.499
ADW17071.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR002489: IPR013027: IPR000103: IPR017900: IPR 017896; KEGG: dps:DP2624 glutamate synthase, beta subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glutamate synthase alpha subunit domain protein; SPTR: Related to glutamate synthase, beta subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; GXGXG motif.
   
 
 0.485
ADW16648.1
Transcriptional regulator, NifA subfamily, Fis Family; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR002078: IPR020441: IPR003018: IPR002197: IPR 003593; KEGG: scl:sce3280 anaerobic nitric oxide reductase transcription regulator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein; SPTR: Sigma-54 dependent transcriptional regulator; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
     
 0.474
ADW17215.1
COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR000795: IPR004161: IPR015190: IPR015191: IPR 013838: IPR005225: IPR004535; KEGG: dak:DaAHT2_0324 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; SPTR: Translation elongation factor, selenocysteine-specific:Small GTP-binding protein domain; TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: Elongat [...]
 
   
 0.454
ADW18474.1
COGs: COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]; InterPro IPR004534: IPR018319; KEGG: dak:DaAHT2_0215 L-seryl-tRNA selenium transferase; PFAM: Pyridoxal phosphate-dependent transferase; PRIAM: L-seryl-tRNA(Sec) selenium transferase; SPTR: L-seryl-tRNA selenium transferase; TIGRFAM: L-seryl-tRNA selenium transferase; PFAM: L-seryl-tRNA selenium transferase; TIGRFAM: seryl-tRNA(sec) selenium transferase.
 
   
 0.410
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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