STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16647.1Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: dak:DaAHT2_2664 transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain. (306 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.760
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.724
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.721
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.685
ADW19022.1
Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: cja:CJA_3147 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase large chain; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.546
ADW16487.1
Selenium metabolism protein YedF; InterPro IPR019870: IPR001455; KEGG: pca:Pcar_0303 redox protein, regulator of disulfide bond formation; PFAM: SirA-like domain-containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA-like protein; DsrE/DsrF-like family; TIGRFAM: selenium metabolism protein YedF.
  
   
 0.487
ADW16648.1
Transcriptional regulator, NifA subfamily, Fis Family; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR002078: IPR020441: IPR003018: IPR002197: IPR 003593; KEGG: scl:sce3280 anaerobic nitric oxide reductase transcription regulator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein; SPTR: Sigma-54 dependent transcriptional regulator; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
     
 0.474
ADW18855.1
COGs: COG0709 Selenophosphate synthase; Contains Selenocysteine; InterPro IPR004536: IPR000421: IPR000728: IPR010918; KEGG: ppd:Ppro_1707 selenide, water dikinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; SPTR: Selenide water dikinase; TIGRFAM: selenide, water dikinase; manually curated; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: selenium donor protein.
 
   
 0.468
ADW17962.1
COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284: IPR007627: IPR007630: IPR000943: IPR 016263; KEGG: dps:DP2192 RNA polymerase sigma-B factor; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; alternative sigma factor RpoH.
    
 
 0.455
ADW17071.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR002489: IPR013027: IPR000103: IPR017900: IPR 017896; KEGG: dps:DP2624 glutamate synthase, beta subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glutamate synthase alpha subunit domain protein; SPTR: Related to glutamate synthase, beta subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; GXGXG motif.
   
 
 0.447
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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