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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16683.1COGs: COG4108 Peptide chain release factor RF-3; InterPro IPR000795: IPR004548: IPR005225: IPR004161; KEGG: pca:Pcar_0583 peptide chain release factor 3; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; SPTR: Peptide chain release factor 3; TIGRFAM: peptide chain release factor 3; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; peptide chain release factor 3. (558 aa)    
Predicted Functional Partners:
rplC
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
    
 0.967
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
  0.965
rpmA
COGs: COG0211 Ribosomal protein L27; InterPro IPR001684; KEGG: dps:DP2591 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.962
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
 
 0.925
rplL
LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
   
 
 0.919
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
   0.919
rpmG
LSU ribosomal protein L33P; InterPro IPR001705: IPR018264; KEGG: gur:Gura_1054 50S ribosomal protein L33; PFAM: ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: ribosomal protein L33; manually curated; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; Belongs to the bacterial ribosomal protein bL33 family.
   
   0.912
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.904
ADW17979.1
COGs: COG0359 Ribosomal protein L9; InterPro IPR020594: IPR020070: IPR020069; KEGG: dak:DaAHT2_1150 ribosomal protein L9; PFAM: Ribosomal protein L9-like; SPTR: Ribosomal protein L9; TIGRFAM: ribosomal protein L9; PFAM: Ribosomal protein L9, N-terminal domain; Ribosomal protein L9, C-terminal domain; TIGRFAM: ribosomal protein L9.
   
   0.904
rplV
LSU ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
    
 
 0.899
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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